It depends on how sick you are. If it's a minor headache then I just usually endure it until it goes away however if it's a fever or something serious then I immediately take meds.
If I'm feeling like garbage I'll take medicine, yeah it tastes nasty but it does help the symptoms of whatever illness you have. Though if it's just a headache I usually power through it, migraines on the other hand nope I take medicine.